Effect of cadmium chloride on the serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH) and androgens in the adult male rat

Gopal Dutt, N. H. and Wakabayashi, K. and Inoue, S. (1978) Effect of cadmium chloride on the serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH) and androgens in the adult male rat. Proceedings of the Indian academy of sciences - section B, experimental biology, 87 (7). pp. 161-167. ISSN 0370-0097

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Abstract

Adult male rats injected with cadmium chloride were compared with controls with respect to serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), androgens and testicular histology. A single injection of cadmium chloride (9 mg/kg) was found to bring about no consistent short term changes in the plasma levels of FSH or LH, but after a long period the levels of both these hormones were elevated. In contrast, the levels of androgen showed a sharp increase at 6 h which declined by 12 h. In accordance with the elevated levels of gonadotropins found at 9-28 days after cadmium chloride injection, the androgen levels showed a drastic reduction. Histological aspect of the testis revealed acute necrotic changes of which the vacuolation of spermatid nuclei and fibrosis of Leydig cells are noteworthy. © 1978 Indian Academy of Sciences.

Item Type: Article
Subjects: B Life Science > Zoology
Divisions: Department of > Zoology
Depositing User: Dhruva Kumar
Date Deposited: 26 May 2021 05:20
Last Modified: 26 May 2021 05:20
URI: http://eprints.uni-mysore.ac.in/id/eprint/13939

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