Preliminary studies on the toxicity and mutagenicity of 1-amino-2-naphthol-4-sulphonic acid in Drosophila melanogaster

Gayathri, M. V. and Krishnamurthy, N. B. (1980) Preliminary studies on the toxicity and mutagenicity of 1-amino-2-naphthol-4-sulphonic acid in Drosophila melanogaster. Journal of Biosciences, 2 (1). pp. 49-54. ISSN 0250-5991

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Abstract

The toxicity and mutagenicity of 1-amino-2-naphtho-4-sulphonic acid were analysed in Drosphila melanogaster. Rate of development and viability were the two parameters employed to study the toxicity. The frequency of dominant lethals was scored to evaluate the mutagenic effect of the chemical on male and female germ cells. Concentrations of 250 mg and above/100 ml wheat cream agar medium were found to be significantly toxic. Significant number of dominant lethals was induced even by a concentration as low as 50 mg/100 ml medium. Male germ cells were more sensitive than female germ cells. © 1980 Indian Academy of Sciences.

Item Type:	Article
Additional Information:	Publisher: Springer India
Uncontrolled Keywords:	development, controlled study, nonhuman, animal experiment, germ cell, dose response, sex difference, arthropod, mutagenicity, chemical mutagenesis, intoxication, drug toxicity, drug response, toxicity, 1 amino 2 naphthol 4 sulfonic acid, dominant lethal test, lethal mutation
Subjects:	B Life Science > Zoology
Divisions:	Department of > Zoology
Depositing User:	Dhruva Kumar
Date Deposited:	12 May 2021 16:05
Last Modified:	12 May 2021 16:05
URI:	http://eprints.uni-mysore.ac.in/id/eprint/13873

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