Vishwanath, B. Sannanaik and Kini, R. Manjunatha and Veerabasappa Gowda, T. (1988) Purification and partial biochemical characterization of an edema inducing phospholipase A2 from Vipera russelli (Russell's viper) snake venom. Toxicon, 26. pp. 713-720.
Full text not available from this repository. (Request a copy)Abstract
A phospholipase A2 (VRV PL-VI) from V. russelli venom was purified to homogeneity in a single step on CM-Sephadex C-25 column. VRV PL-VI is a basic protein with a mol. weight �12,000 and showed a basic pH optimum (7.3-8.0) and a high temperature optimum (75°). It hydrolyzed purified phospholipids in the order of phosphatidylethanolamine \textgreater phosphatidylcholine � phosphatidylserine \textgreater phosphatidylinositol = 0. LD50 (i.p.) is 3.5 μg/g in mice. The phospholipase A2 induces persistent edema in the mouse foot pad.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | phospholipase A2 property viper venom, methodology, nonhuman, animal experiment, Mice, mouse, Animal, edema, enzyme purification, viper venom, Chromatography, Human, Edema, Lethal Dose 50, Non-U.S. Gov't, phospholipase a2, Phospholipases A, snake, snake venom, Support, Viper Venoms, Electrophoresis, Gel, ld 50, Molecular Weight, Polyacrylamide Gel, Phospholipases, reptile |
| Subjects: | C Chemical Science > Biochemistry |
| Divisions: | Department of > Biochemistry |
| Depositing User: | Dhruva Kumar |
| Date Deposited: | 05 May 2021 11:54 |
| Last Modified: | 12 Jul 2022 06:06 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/13156 |
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