Allelic variants of DYX1C1 are not associated with dyslexia in India.

Saviour, P. and Satish Kumar, and Kiran, U. and Ravuri, R. R. and Rao, V. R. and Ramachandra, N. B. (2008) Allelic variants of DYX1C1 are not associated with dyslexia in India. Indian Journal of Human Genetics, 14 (3, Cop). pp. 99-102. ISSN 0971-6866

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Abstract

Dyslexia is a hereditary neurol. disorder that manifests as an unexpected difficulty in learning to read despite adequate intelligence, education, and normal senses. The prevalence of dyslexia ranges from 3 to 15% of the school aged children. Many genetic studies indicated that loci on 6p21.3, 15q15-21, and 18p11.2 have been identified as promising candidate gene regions for dyslexia. Recently, it has been suggested that allelic variants of gene, DYX1C1 influence dyslexia. In the present study, exon 2 and 10 of DYX1C1 has been analyzed to verify whether these single nucleotide polymorphisms (SNPs) influence dyslexia, in our population. Our study identified 4 SNPs however, none of these SNPS were found to be significantly assocd. with dyslexia suggesting DYX1C1 allelic variants are not assocd. with dyslexia. [on SciFinder(R)]

Item Type: Article
Additional Information: Unmapped bibliographic data: PY - 2008/// [EPrints field already has value set] JA - Indian J. Hum. Genet. [Field not mapped to EPrints]
Uncontrolled Keywords: DYX1C1 allele polymorphism dyslexia population
Subjects: Agriculture Biological Sciences > Zoology
University of Mysore > PG Campuses > Manasagangotri, Mysore > Agriculture Biological Sciences > Zoology
Divisions: PG Campuses > Manasagangotri, Mysore > Zoology
Depositing User: Dhruvakumar
Date Deposited: 10 Jun 2013 05:47
Last Modified: 23 Aug 2013 07:08
URI: http://eprints.uni-mysore.ac.in/id/eprint/12202

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