Rapid spectrophotometric determination of sulphonamide derivatives with resorcinol.

Nagaraja, P. and Sunitha, K. R. and Vasantha, R. A. and Yathirajan, H. S. (2002) Rapid spectrophotometric determination of sulphonamide derivatives with resorcinol. Indian Journal of Pharmaceutical Sciences, 64 (4, Cop). pp. 391-393. ISSN 0250-474X

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A rapid and simple spectrophotometric method for the detn. of sulpha drugs was described. The method is based on the formation of a red colored azo product by the diazotization of sulfonamides, sulfamethoxazole, sulfadiazine and sulfacetamide followed by a coupling reaction with resorcinol. Absorbance of the resulting red azo product is measured at 500 nm. Beer's law is obeyed in the concn. range of 0.25-7.0 μg/mL at the wavelength of max. absorption. The method was successfully employed for the detn. of sulfonamides in various pharmaceutical prepns. [on SciFinder(R)]

Item Type: Article
Additional Information: Unmapped bibliographic data: PY - 2002/// [EPrints field already has value set] JA - Indian J. Pharm. Sci. [Field not mapped to EPrints]
Uncontrolled Keywords: sulfadiazine sulfamethoxazole sulfacetamide detn spectroscopy
Subjects: Physical Sciences > Chemistry
Divisions: PG Campuses > Manasagangotri, Mysore > Chemistry
Depositing User: Praveen Kumari B.L
Date Deposited: 30 May 2013 11:15
Last Modified: 30 May 2013 11:16
URI: http://eprints.uni-mysore.ac.in/id/eprint/11754

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