N-[(2′-Cyano­bi­phenyl-4-yl)­methyl]- L -valine methyl ester hydro­chloride: an intermediate in the synthesis of valsartan

Yathirajan, H. S. and Nagaraj, B. and Gaonkar, Santosh L. and Narasegowda, R. S. and Nagaraja, P. and Prabhuswamy, B. and Bolte, Michael (2004) N-[(2′-Cyano­bi­phenyl-4-yl)­methyl]- L -valine methyl ester hydro­chloride: an intermediate in the synthesis of valsartan. Acta Crystallographica Section E, 60 (11). o2160-o2162. ISSN 2056-9890

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Abstract

The title compound {systematic name: methyl 2-[(2′-cyano­bi­phenyl-4-yl)­methyl­ammonio]-3-methyl­butanoate chloride}, C20H23N2O2+·Cl−, is a key intermediate in the synthesis of valsartan. It crystallizes with two ion pairs in the asymmetric unit, related pseudocentrosymmetrically to each other. The two cations differ only in the orientation of the iso­propyl group.

Item Type:	Article
Subjects:	C Chemical Science > Chemistry
Divisions:	Department of > Chemistry
Depositing User:	C Swapna Library Assistant
Date Deposited:	17 Dec 2019 06:14
Last Modified:	16 Jul 2022 07:15
URI:	http://eprints.uni-mysore.ac.in/id/eprint/10238

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