Kumara, M. N. and Chenne Gowda, D. and Rangappa, K. S. (2001) Synthesis and kinetics of oxidation of phenylalanylglycine, isoleucyl-glycine, and leucyl-glycine with anodically generated manganese(III) sulfate. A mechanistic study. Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry, 31 (10). pp. 1771-1785.
![[img]](http://eprints.uni-mysore.ac.in/style/images/fileicons/text.png) |
Text (Full Text)
Che_2001_Kumar MN.pdf - Published Version Restricted to Registered users only Download (321kB) | Request a copy |
Abstract
The kinetics of oxidation of dipeptides (DP), namely phenylalanyl-glycine (Phe-Gly), isoleucyl-glycine (Ile-Gly) and leucyl-glycine (Leu-Gly), by Mn(III) have been studied in the presence of sulfate ions in acidic solution at 26 degreesC. The reaction was followed spectrophotometrically lambda(max) = 500 nm. A first-order dependence of the rate on both Mn(III)] and DP] was observed. The rate is independent of the concentration of reduction product, Mn(II) and hydrogen ions. The effects of varying the dielectric constant of the medium and addition of anions such as sulfate, chloride and perchlorate were studied. The activation parameters have been evaluated using Arrhenius and Eyring plots. The oxidation products were isolated and characterized. A mechanism involving the reaction of DP with Mn(III) in the rate limiting step is suggested.
| Item Type: | Article |
|---|---|
| Subjects: | C Chemical Science > Chemistry |
| Divisions: | Department of > Chemistry |
| Depositing User: | Harisha R uom |
| Date Deposited: | 10 Jan 2020 11:21 |
| Last Modified: | 02 Jul 2022 10:22 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/10158 |
Actions (login required)
 |
View Item |
