Oxidimetric determination of isoniazid and amino acids with bromamine-B in buffer medium

Raju, C. R. and Yathirajan, H. S. and Rangappa, K. S. and Mohana, K. N. and Rai, K. M. Lokanatha (2001) Oxidimetric determination of isoniazid and amino acids with bromamine-B in buffer medium. Oxidation Communications, 24 (3). pp. 393-399.

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Abstract

Bromamine-B oxidises isoniazid, glutathione, glycine, leucine, isoleucine, valine, alanine, phenylalanine, threonine and glutamine stoichiometrically in pH 5 (pH 6 for isoleucine and threonine) acetate buffer medium with a four-electron change (six-electron change for glycine and ten-electron change for glutathione). Back-titration procedures have been developed for the determination of isoniazid and amino acids. The products have been identified. The method has been successfully employed for the determination of isoniazid in pharmaceutical preparations and also for the estimation of metal complexes of glutathione and metal salts of glycine and alanine.

Item Type: Article
Uncontrolled Keywords: bromamine-B (BAB); oxidation; isoniazid; amino acids
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: Harisha R uom
Date Deposited: 10 Jan 2020 11:00
Last Modified: 13 Jan 2023 10:51
URI: http://eprints.uni-mysore.ac.in/id/eprint/10156

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